Searchable abstracts of presentations at key conferences in endocrinology

ea0083erco6 | Endocrine-related Cancer | EYES2022

Outcome of immuncheckpoint inhibitor therapy in adrenocortical carcinoma – A multicenter retrospective study

H Remde , L Schmidt-Pennington , M Reuter , L Landwehr , M Jensen , H Lahner , K Laubner , J Schreiner , J Bojunga , S Kircher , A Pohrt , M. V. Teleanu , D Hubschmann , A Stenzinger , H Glimm , S Frohling , M Fassnacht , K Mai , M. Kroiss

Background: Adrenocortical carcinoma is a rare endocrine malignancy with poor prognosis and few treatment options in advanced disease. Immune checkpoint inhibitors (ICI) have been studied in few clinical trials with a limited number of patients in ACC. No real-life data are available so far. In the present study we aimed at evaluating treatment response and safety of ICI treatment in advanced ACC and identifying clinical, biochemical, histological and molecular markers for pre...